Is Melanotan II safe?
Case reports of harm; no long-term data
CAnimal and cell studiesNot approvedas of 2026-10-26
The pilot study and case reports show these acute effects: nausea, flushing, fatigue, appetite loss and long erections. Moles often darken or change. Dermatologists have warned that melanoma could be missed or even promoted. Nobody regulates the products, so users do not know what they inject. No data exist on long-term use or on cancer risk over years. 1235
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Citations
- FDA: Certain bulk drug substances for use in compounding may present significant safety risks fda.gov
- Dorr 1996, Life Sci: Evaluation of melanotan-II in a pilot phase 1 clinical study pubmed.ncbi.nlm.nih.gov
- 2008, Arch Dermatol: Melanotan-associated changes in melanocytic nevi doi.org
- 2009, Br J Dermatol: Melanotan II use and atypical naevi doi.org
- 2014, Dermatology: Melanoma associated with the use of melanotan-II pubmed.ncbi.nlm.nih.gov
Reference information only, not medical advice. Drawn from the Melanotan II article, fact-checked against the cited sources. No dosing anywhere on this site.