Peptide Graded

Acetyl octapeptide-3

Is Acetyl octapeptide-3 safe?

No published safety assessment

CAnimal and cell studiesCosmetic ingredientas of 2026-10-26

The published patch study reported no adverse effects. Cosmetic peptides of this type are generally well tolerated on the skin. Argireline has a published Cosmetic Ingredient Review safety assessment, but SNAP-8 does not. There are also no data on what happens if a meaningful amount does cross the skin. 4

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More on Acetyl octapeptide-3

Citations

  1. Wang 2013, Am J Clin Dermatol: argireline (acetyl hexapeptide-8) for peri-orbital wrinkles, randomized placebo-controlled study doi.org
  2. FDA: how cosmetics are regulated but not approved fda.gov
  3. FDA: is it a cosmetic, a drug, or both? fda.gov
  4. Shin 2024, Ann Dermatol: dissolving microneedle patch containing acetyl octapeptide-3, split-face placebo-controlled study pubmed.ncbi.nlm.nih.gov

Reference information only, not medical advice. Drawn from the Acetyl octapeptide-3 article, fact-checked against the cited sources. No dosing anywhere on this site.