Peptide Graded

Cosyntropin

Is Cosyntropin safe?

Label data; single-dose use

AStrong human evidenceFDA approvedas of 2026-10-26

Cosyntropin is given once. So side effects are rare and brief. The label lists hypersensitivity reactions, including rash, flushing and, rarely, anaphylaxis. It also lists brief bradycardia, tachycardia or hypertension. People who have had an allergic reaction to ACTH products are most at risk. There are no long-term safety questions, because there is no long-term exposure. 2

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Citations

  1. Kazlauskaite 2008, J Clin Endocrinol Metab: corticotropin tests for hypothalamic-pituitary-adrenal insufficiency, meta-analysis doi.org
  2. FDA label, 2023: Cortrosyn (cosyntropin for injection) accessdata.fda.gov

Reference information only, not medical advice. Drawn from the Cosyntropin article, fact-checked against the cited sources. No dosing anywhere on this site.