Peptide Graded

Dasiglucagon

Is Dasiglucagon safe?

Trial and label safety data

AStrong human evidenceFDA approvedas of 2026-10-26

The common side effects in trials were nausea, vomiting, headache, diarrhoea and pain where the shot went in. Glucagon and the swing in sugar both cause these. The label warns of three risks. Dasiglucagon can release catecholamines from a pheochromocytoma (an adrenal tumour) and cause a hypertensive crisis. It can trigger insulin release from an insulinoma and worsen hypoglycemia. Allergic reactions have occurred with glucagon products. 12

The drug is used once in an emergency, so there are no long-term exposure questions. The label does not include data in children under 20 kg. 2

Read the full Dasiglucagon page

More on Dasiglucagon

Citations

  1. Pieber 2021, Diabetes Care: dasiglucagon for severe hypoglycemia, phase 3 randomized double-blind trial doi.org
  2. FDA label, June 2026: Zegalogue (dasiglucagon) injection accessdata.fda.gov

Reference information only, not medical advice. Drawn from the Dasiglucagon article, fact-checked against the cited sources. No dosing anywhere on this site.