Peptide Graded

Echinocandins

Is Echinocandins legal in the US?

Yes, FDA approved for serious yeast infections such as Candida in the blood.

AStrong human evidenceFDA approvedas of 2026-10-26

Approved. Four echinocandins are FDA-approved antifungals: caspofungin (Cancidas, 2001), micafungin (Mycamine, 2005), anidulafungin (Eraxis, 2006) and rezafungin (Rezzayo, 2023). Their indications center on candidemia, invasive and esophageal candidiasis, with caspofungin also approved for empiric therapy in febrile neutropenia and for aspergillosis refractory to other drugs, and micafungin for prophylaxis in stem-cell transplant recipients. 123

Yes. Caspofungin, micafungin, anidulafungin and rezafungin are all approved, chiefly for candidemia and invasive candidiasis. Caspofungin has added approved uses: treatment of suspected fungal infection in febrile neutropenia, and salvage treatment of aspergillosis. Micafungin is also approved to prevent infection in stem-cell transplant. 123

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Citations

  1. Mora-Duarte 2002, NEJM: comparison of caspofungin and amphotericin B for invasive candidiasis doi.org
  2. Reboli 2007, NEJM: anidulafungin versus fluconazole for invasive candidiasis doi.org
  3. Rezzayo (rezafungin) prescribing information drugs.com

Reference information only, not medical advice. Drawn from the Echinocandins article, fact-checked against the cited sources. No dosing anywhere on this site.