Is IGF-1 LR3 safe?
No human safety data
CAnimal and cell studiesNot approvedas of 2026-10-26
Human safety data do not exist. The hazards would be those of unopposed IGF-1 activity. These are low blood sugar (hypoglycaemia), swelling and joint pain. There is also a theoretical risk of promoting tumours, since IGF-1 signalling is a growth and survival signal for cancer cells. Laboratory-grade material is not made to be sterile or free of fever-causing contaminants (pyrogens) for injection. 13
More on IGF-1 LR3
Citations
- Hakuno and Takahashi 2018, Journal of Molecular Endocrinology: IGF1 receptor signaling pathways pubmed.ncbi.nlm.nih.gov
- Scientific Reports 2019: experimental study using IGF-1 LR3 doi.org
- Frontiers in Endocrinology 2026: review covering IGF-1 analogs doi.org
Reference information only, not medical advice. Drawn from the IGF-1 LR3 article, fact-checked against the cited sources. No dosing anywhere on this site.