Peptide Graded

Lanreotide

Is Lanreotide safe?

No excess serious events in 96 weeks

AStrong human evidenceFDA approvedas of 2026-10-26

The label lists these common side effects: diarrhea, belly pain, gallstones (cholelithiasis) and injection-site reactions. Lanreotide can lower or raise blood sugar. It can slow the heart rate and reduce thyroid function. So the label calls for checks of glucose, heart rate and thyroid tests. Gallbladder problems are common enough that doctors sometimes do imaging before and during treatment. 2

CLARINET found no excess of serious side effects compared with placebo over two years. Diarrhea and high blood sugar were the main differences. Long-term data in children or pregnant patients are limited. 12

Diarrhea, belly pain, gallstones, and lumps or pain at the injection site. Blood sugar can move in either direction. The heart rate can slow. So the label asks for checks. 2

Read the full Lanreotide page

More on Lanreotide

Citations

  1. Caplin 2014, NEJM: Lanreotide in metastatic enteropancreatic neuroendocrine tumors (CLARINET) doi.org
  2. Somatuline Depot (lanreotide) US prescribing information, revised July 2024 (Drugs.com) drugs.com

Reference information only, not medical advice. Drawn from the Lanreotide article, fact-checked against the cited sources. No dosing anywhere on this site.