Is Palmitoyl tetrapeptide-7 safe?
Industry safety review: safe in cosmetics
In 2018 the Cosmetic Ingredient Review panel assessed palmitoyl tetrapeptide-7, along with tripeptide-1 and hexapeptide-12. It found the peptide safe at the doses used in cosmetics. These are usually a few parts per million. No reactions linked to it have been reported. The review covers safety only. 1
The 2018 safety review found no irritation or sensitization concern at cosmetic doses. Peptides this small rarely cause reactions. But a finished product can still irritate skin through its other ingredients. 1
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Citations
- Johnson 2018 (Cosmetic Ingredient Review), Int J Toxicol: safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 pure.psu.edu
- FDA: how cosmetics are not FDA-approved but are FDA-regulated fda.gov
Reference information only, not medical advice. Drawn from the Palmitoyl tetrapeptide-7 article, fact-checked against the cited sources. No dosing anywhere on this site.