Peptide Graded

Palmitoyl tripeptide-38

Is Palmitoyl tripeptide-38 legal in the US?

No prescription; it is a cosmetic ingredient.

CAnimal and cell studiesCosmetic ingredientas of 2026-10-26

Palmitoyl tripeptide-38 is a cosmetic ingredient, sold as Matrixyl Synthe'6, and is not approved by the FDA as a drug for any use. The FDA does not approve cosmetic ingredients before sale. 2

No. It is a cosmetic ingredient. The FDA regulates it but does not approve it. A product containing it that claimed to treat a skin condition would be an unapproved drug. 2

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More on Palmitoyl tripeptide-38

Citations

  1. Lintner 2020, J Cosmet Dermatol: a serum containing vitamins C and E and a matrix-repair tripeptide improves photoaged skin, open-label study doi.org
  2. FDA: how cosmetics are not FDA-approved but are FDA-regulated fda.gov

Reference information only, not medical advice. Drawn from the Palmitoyl tripeptide-38 article, fact-checked against the cited sources. No dosing anywhere on this site.