Is Histrelin legal in the US?
Yes, FDA approved for puberty that starts too early in children.
BSome human evidenceFDA approvedas of 2026-10-26
Histrelin is FDA-approved as Supprelin LA, a 12-month subcutaneous implant for central precocious puberty in children, approved in 2007. The prostate cancer implant Vantas, approved in 2004, was discontinued by its manufacturer in 2021, so Supprelin LA is the only histrelin product on the US market. 23
Yes. Supprelin LA has been approved since 2007 for central precocious puberty. Vantas was the prostate cancer version, approved in 2004. It was discontinued in 2021 and is no longer available. 23
More on Histrelin
Citations
- Eugster 2007, Journal of Clinical Endocrinology and Metabolism: histrelin subdermal implant in children with central precocious puberty, 12-month results doi.org
- Endo: Supprelin LA (histrelin acetate) prescribing information endodocuments.com
- MDedge/KHN: patients lose cheaper option as Vantas is discontinued mdedge.com
Reference information only, not medical advice. Drawn from the Histrelin article, fact-checked against the cited sources. No dosing anywhere on this site.