Is Oligopeptide-1 legal in the US?
No prescription; it is a cosmetic ingredient.
CAnimal and cell studiesCosmetic ingredientas of 2026-10-26
Oligopeptide-1 is the cosmetic ingredient name for epidermal growth factor. In skincare it is regulated as a cosmetic and is not approved by the FDA as a drug for any use; the FDA does not approve cosmetic ingredients before sale. 23
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Citations
- Seidel 2015, J Drugs Dermatol: reduced appearance of under-eye bags with twice-daily application of EGF serum, a pilot study pubmed.ncbi.nlm.nih.gov
- FDA: how cosmetics are not FDA-approved but are FDA-regulated fda.gov
- FDA: is it a cosmetic, a drug, or both? fda.gov
Reference information only, not medical advice. Drawn from the Oligopeptide-1 article, fact-checked against the cited sources. No dosing anywhere on this site.