Is Palmitoyl tripeptide-1 safe?
2018 CIR review found it safe in cosmetics
DNo meaningful dataCosmetic ingredientas of 2026-10-26
The Cosmetic Ingredient Review panel reviewed tripeptide-1 and its fatty acyl derivatives in 2018. That includes the palmitoyl form. It concluded they are safe in cosmetics at current use concentrations. No specific adverse reactions have been reported. The review covers safety. It says nothing about whether the ingredient works. 1
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Citations
- Cosmetic Ingredient Review 2018, Int J Toxicol: safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 pure.psu.edu
- FDA: how cosmetics are not FDA-approved but are FDA-regulated fda.gov
Reference information only, not medical advice. Drawn from the Palmitoyl tripeptide-1 article, fact-checked against the cited sources. No dosing anywhere on this site.