Is Pentapeptide-18 legal in the US?
No prescription; it is a cosmetic ingredient.
CAnimal and cell studiesCosmetic ingredientas of 2026-10-26
Pentapeptide-18 is a cosmetic ingredient, sold under the trade name Leuphasyl. Cosmetic ingredients in the United States are not reviewed or approved by the FDA before sale, so there is no FDA approval to cite for or against it. 2
No. The FDA does not approve cosmetic ingredients in the United States before they are sold. It can act against a cosmetic that is unsafe or makes drug claims. But there is no approval to look up for pentapeptide-18. 2
Read the full Pentapeptide-18 page
More on Pentapeptide-18
Citations
- Dragomirescu 2014, Cosmetics (MDPI): the efficiency and safety of Leuphasyl, a botox-like peptide mdpi.com
- SpecialChem: Lubrizol Leuphasyl (pentapeptide-18) product listing specialchem.com
- Pawłowska 2024, Life: retinol and pentapeptide-18 loaded lipid nanocarriers in anti-acne and anti-aging creams doi.org
Reference information only, not medical advice. Drawn from the Pentapeptide-18 article, fact-checked against the cited sources. No dosing anywhere on this site.