Is Secretin safe?
Label data, well tolerated
BSome human evidenceFDA approvedas of 2026-10-26
As a single diagnostic dose, secretin is well tolerated. A 531-patient open-label trial is summarized in the label. The most common reactions were nausea, vomiting, flushing and upset stomach. Each affected only a few patients. Anticholinergic drugs can blunt the pancreatic response and distort the test result. Doctors stop them beforehand. In the autism trial, no child had adverse effects that limited treatment. 12
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Reference information only, not medical advice. Drawn from the Secretin article, fact-checked against the cited sources. No dosing anywhere on this site.