Is Tripeptide-10 citrulline legal in the US?
No prescription; it is a cosmetic ingredient.
DNo meaningful dataCosmetic ingredientas of 2026-10-26
Tripeptide-10 citrulline is a cosmetic ingredient and falls outside FDA drug approval. Cosmetics do not need pre-market approval; the ingredient has not been reviewed as a drug for any claim. 1
It does not need to be. The FDA does not approve cosmetic ingredients before sale. The manufacturer is responsible for safety. No drug claims have been evaluated. 1
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More on Tripeptide-10 citrulline
Citations
- Puig 2008, Int J Cosmet Sci: A new decorin-like tetrapeptide for optimal organization of collagen fibres doi.org
Reference information only, not medical advice. Drawn from the Tripeptide-10 citrulline article, fact-checked against the cited sources. No dosing anywhere on this site.