Peptide Graded

Ecallantide

Is Ecallantide legal in the US?

Yes, FDA approved for sudden attacks of hereditary angioedema.

AStrong human evidenceFDA approvedas of 2026-10-26

Approved. Ecallantide is sold as Kalbitor, approved by the FDA in December 2009 for acute attacks of hereditary angioedema, originally in patients 16 and older and extended in 2014 to patients 12 and older. It carries a boxed warning for anaphylaxis and must be given by a healthcare professional. 2

Yes. Kalbitor was approved in 2009 for sudden hereditary angioedema attacks in patients 16 and older. In 2014 the age limit dropped to 12. 2

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More on Ecallantide

Citations

  1. Cicardi 2010, NEJM: ecallantide for the treatment of acute attacks in hereditary angioedema (EDEMA3) doi.org
  2. Kalbitor (ecallantide) prescribing information drugs.com

Reference information only, not medical advice. Drawn from the Ecallantide article, fact-checked against the cited sources. No dosing anywhere on this site.